Furoscix (furosemide) injection, manufactured by scPharmaceuticals, has been approved to help adults manage congestion caused by fluid overload in chronic heart failure. This innovative treatment utilizes a special formulation of furosemide delivered through an On-Body Infusor, providing an 80-mg dose that mirrors the effects of intravenous diuretics.
What is Furoscix?
FUROSCIX is an at-home treatment for fluid buildup associated with heart failure, designed for easy use with or without a caregiver. It delivers furosemide, a commonly used diuretic, through a wearable device, providing a quick reset of the patient’s body fluid levels. The treatment is not intended for chronic use or as a replacement for daily oral diuretics.
How does Furoscix work?
FUROSCIX is provided as a comprehensive kit delivered directly to patients’ homes. The kit includes:
● The FUROSCIX Instructions for Use
● One cartridge of medicine
● A one-time-use device that is preset for your treatment
● Alcohol wipes
The FUROSCIX On-Body Infusor administers a fixed dose of 80 mg of furosemide over approximately five hours. This device delivers the medication just under the skin (subcutaneously). When activated, a small needle inserts into the skin to administer the medication. The On-Body Infusor signals once all the medication has been delivered. Upon removal from the skin, a needle cover automatically extends to prevent accidental needle sticks.
See full instructions for FUROSCIX On-Body Infusor here.
Side Effects of Furoscix
Potential side effects of Furoscix may include:
● Lose excess water and electrolytes (dehydration)
● Low blood pressure (lightheadedness, dizziness)
● High blood sugar
● Loss of hearing (ringing in ears)
● Sensitivity to sunlight
● Administration site and skin reactions (bruising, redness, swelling, and infusion site pain)
Cost of Furoscix
The out-of-pocket cost can vary depending on the pharmacy and any available discounts. FUROSCIX Direct offers services to help reduce out-of-pocket costs for eligible patients, including co-pay support and patient assistance programs. A FUROSCIX Direct representative can provide more detailed information about your options.
Furoscix vs. Lasix
FUROSCIX and Lasix are both medications that contain the active ingredient furosemide. FUROSCIX achieved similar drug levels as IV furosemide but it is administered through the skin. Your care team should give you directions on how to take your oral diuretics during and after treatment with FUROSCIX.
Drug Name | Furoscix | Lasix |
Active Ingredient | Furosemide | Furosemide |
Inactive Ingredient | Hydrochloric acid for pH adjustment if needed, sodium chloride (5.84 mg), sodium hydroxide for pH adjustment if needed, tris HCl (7.88 mg), and water for injection (q.s.) | Lactose monohydrate, magnesium stearate, starch, corn, talc, silicon dioxide |
Dosing | 80 mg per 10 mL | Oral Dosing: 20-600 mg per day IV/IM Dosing: 20-200 mg per dose, with potential higher doses in some cases. |
Formulation | Subcutaneous (SC) | Orally (tablets), Intravenous (IV), Intramuscularly (IM) |
Indication | Treatment of congestion due to fluid overload in adults with chronic heart failure | Edema, hypertension |
Administration | Outpatient setting | Hospital or outpatient setting |
Read the full Furoscix package insert here.
Conclusion
Furoscix represents an advancement in the management of congestion due to fluid overload in adults with chronic heart failure. By offering a convenient at-home treatment option through a wearable On-Body Infusor, it provides congestion relief without hospital visits, enhancing patient comfort and compliance. As the medical community continues to embrace such technologies, Furoscix stands out as a promising solution for managing heart failure symptoms effectively and efficiently.
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